AKT1 Antibody from BIORBYT LTD.

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Antigenic SpecificityAKT1
CloneAKT1/3898R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG
FormatProtein A purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsELISA, WB
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DescriptionRecognizes a protein of 62kDa, which is identified as AKT1. The serine/threonine kinase Akt family contains several members, including Akt1 (also designated PKB or RacPK), Akt2 (also designated PKB tyrosine residues 740 and 751, which bind the subunit of the phosphatidylinositol 3-kinase (PI 3-kinase) complex. Activation of Akt1 by insulin or insulin-growth factor-1 (IGF-1) results in phosphorylation of both Thr 308 and Ser 473. Akt proteins become phosphorylated and activated in insulin/IGF-1-stimulated cells by an upstream kinase(s), and the activation of Akt1 and Akt2 is inhibited by the PI kinase inhibitor wortmannin.
ImmunogenA portion of amino acids 85-189 from the human protein was used as the immunogen for the recombinant AKT1 antibody.
Other Namesn/a
Gene, Accession #UniProt: P31749
Catalog #orb699554
Price$764
Order / More InfoAKT1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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