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Antigenic Specificity | SNW1 / NCoA-62 / SKIP |
Clone | PCRP-SNW1-1C12 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | FACS, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nuclear receptor coactivator NCOA62/SNW1 (also called Nuclear Protein SkiP, SKIIP, Ski-interacting protein) is a member of the SNW gene family, encodes a coactivator that enhances transcription from some Pol II promoters. This coactivator can bind to the ligand-binding domain of the vitamin D receptor and to retinoid receptors to enhance vitamin D-, retinoic acid-, estrogen-, and glucocorticoid-mediated gene expression. It can also interact with poly(A)-binding protein 2 to directly control the expression of muscle-specific genes at the transcriptional level. Finally, the protein may be involved in oncogenesis since it interacts with a region of SKI oncoproteins that is required for transforming activity. |
Immunogen | A recombinant fragment of human SNW1 protein was used as the immunogen for the SNW1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: Q13573 |
Catalog # | orb1825524 |
Price | $405 |
Order / More Info | SNW1 / NCoA-62 / SKIP Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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