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Antigenic Specificity | Phospho-Raf1 (Ser259) |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. |
Immunogen | A synthetic phosphopeptide corresponding to residues surrounding Ser259 of human Raf1 |
Other Names | RAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1 |
Gene, Accession # | Gene ID: 5894, UniProt: P04049 |
Catalog # | orb1733067 |
Price | $345 |
Order / More Info | Phospho-Raf1 (Ser259) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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