Phospho-Raf1 (Ser259) Antibody from BIORBYT LTD.

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Antigenic SpecificityPhospho-Raf1 (Ser259)
Clonemonoclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
IsotypeIgG
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsIHC, WB
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DescriptionRaf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2.
ImmunogenA synthetic phosphopeptide corresponding to residues surrounding Ser259 of human Raf1
Other NamesRAF1; RAF; RAF proto-oncogene serine/threonine-protein kinase; Proto-oncogene c-RAF; cRaf; Raf-1
Gene, Accession #Gene ID: 5894, UniProt: P04049
Catalog #orb1733067
Price$345
Order / More InfoPhospho-Raf1 (Ser259) Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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