LIM Kinase 2 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-LIM Kinase 2 antibody, protein, ELISA kits.
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| Antigenic Specificity | LIM Kinase 2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | n/a |
| Applications | ICC, IHC, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Serine/threonine-protein kinase that plays an essential role in the regulation of actin filament dynamics (PubMed:10436159, PubMed:11018042). Acts downstream of several Rho family GTPase signal transduction pathways (PubMed:10436159, PubMed:11018042). Involved in astral microtubule organization and mitotic spindle orientation during early stages of mitosis by mediating phosphorylation of TPPP (PubMed:22328514). Displays serine/threonine-specific phosphorylation of myelin basic protein and histone (MBP) in vitro (PubMed:8537403). Suppresses ciliogenesis via multiple pathways; phosphorylation of CFL1, suppression of directional trafficking of ciliary vesicles to the ciliary base, and by facilitating YAP1 nuclear localization where it acts as a transcriptional corepressor of the TEAD4 target genes AURKA and PLK1 (PubMed:25849865). |
| Immunogen | Synthetic peptide of human LIMK2 |
| Other Names | LIM domain kinase 2 |
| Gene, Accession # | Gene ID: 3985, UniProt: P53671 |
| Catalog # | orb1730083 |
| Price | $296 |
| Order / More Info | LIM Kinase 2 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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