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Antigenic Specificity | APOB / Apolipoprotein B |
Clone | APOB/4333 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by APOBEC1 (also designated human (or rat) small intestinal apolipoprotein B mRNA editing protein, HEPR or REPR) in hepatic cells to achieve a steady state proportion of edited and unedited RNA molecules. Two forms of apoB are known to circulate in the plasma of mammals. ApoB-100 is a protein primarily synthesized in the liver as a structural component of very low density lipoprotein particles. A truncated form of apoB-100, apoB-48, is synthesized in the small intestine and contains the amino-terminal 2,152 amino acids of the larger protein. This organ-specific partitioning of apoB production is the resultof RNA editing of a common apoB gene. |
Immunogen | A portion of amino acids 592-689 from the human protein was used as the immunogen for the Apolipoprotein B antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P04114 |
Catalog # | orb699676 |
Price | $405 |
Order / More Info | APOB / Apolipoprotein B Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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