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Antigenic Specificity | Phospho-KCNQ2/3/4/5 (Thr217/Thr246/Thr223/Thr251) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | ELISA, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and a related protein encoded by the KCNQ3 gene, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in KCNQ2 are a cause of benign familial neonatal convulsions type 1 (BFNC), also known as epilepsy, benign neonatal type 1 (EBN1). At least five transcript variants encoding five different isoforms have been found for this gene. |
Immunogen | The antiserum was produced against synthesized peptide derived from human Kv7.3/KCNQ3 around the phosphorylation site of Thr246. AA range:191-240 |
Other Names | KCNQ2; Potassium voltage-gated channel subfamily KQT member 2; KQT-like 2; Neuroblastoma-specific potassium channel subunit alpha KvLQT2; Voltage-gated potassium channel subunit Kv7.2; KCNQ3; Potassium voltage-gated channel subfamily KQT me |
Gene, Accession # | Gene ID: 3786, UniProt: Q9NR82 |
Catalog # | orb1730631 |
Price | $296 |
Order / More Info | Phospho-KCNQ2/3/4/5 (Thr217/Thr246/Thr223/Thr251) Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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