DKK1 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | DKK1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to DKK1.Dickkopf-related protein 1 (DKK1) belongs to the dickkopf family. DKK1 is a secreted protein thatinduces anterior development by antagonizing canonical Wnt signaling upstream of its effect on betacateninregulation. DKK1 inhibits LRP5/6 interaction with Wnt and by forming a ternary complex withthe transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play animportant role in vertebrate development, where they locally inhibit Wnt regulated processes such asantero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult,Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
| Immunogen | N-terminal region of human DKK1 |
| Other Names | DKK1,Dickkopfrelated protein 1,Dickkopf1,Dkk1,hDkk1,SK |
| Gene, Accession # | UniProt: O94907 |
| Catalog # | orb67138 |
| Price | $527 |
| Order / More Info | DKK1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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