MyoD1 Antibody from BIORBYT LTD.

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Antigenic SpecificityMyoD1
CloneMYOD1/2075R
Host SpeciesRecombinant Rabbit
Reactive Specieshuman
IsotypeIgG, kappa
FormatProtein A purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionMyoD, or MYOD1, is one of the earliest markers of myogenic commitment. MyoD is expressed at extremely low and essentially undetectable levels in quiescent satellite cells, but expression of MyoD is activated in response to exercise or muscle tissue damage. The effect of MyoD on satellite cells is dose-dependent; high MyoD expression represses cell renewal, promotes terminal differentiation and can induce apoptosis. Although MyoD marks myoblast commitment, muscle development is not dramatically ablated in mouse mutants lacking the MyoD gene. This is likely due to functional redundancy from Myf5 and/or Mrf4. Nevertheless, the combination of MyoD and Myf5 is vital to the success of myogenesis. [Wiki]
ImmunogenRecombinant human protein was used as the immunogen for this recombinant MyoD antibody.
Other Namesn/a
Gene, Accession #UniProt: P15172
Catalog #orb606486
Price$764
Order / More InfoMyoD1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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