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Antigenic Specificity | MMP2 |
Clone | MMP2/4586 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | It recognizes a protein of 72kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway. |
Immunogen | Recombinant human protein was used as the immunogen for the Matrix metalloproteinase 2 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P08253 |
Catalog # | orb1825290 |
Price | $405 |
Order / More Info | MMP2 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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