CD100 Antibody from BIORBYT LTD.

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Antigenic SpecificityCD100
Clone133-1C6
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgM
Formatfluorescein (FITC) conjugate
Size100 tests
Concentrationn/a
ApplicationsFC
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DescriptionCD100, also known as semaphorin 4D, is a homodimerizing type I transmembrane glycoprotein containing an extracellular semaphorin domain. It is expressed on most hematopoietic cells with the exception of immature bone marrow cells, erythrocytes and platelets. A 120 kDa soluble form is generated from the transmembrane form by proteolytic cascade following primary T and B cell activation. It seems CD100 acts through dampening CD72-mediated negative signaling. CD100 promotes angiogenesis, invasive growth, proliferation and anti-apoptosis of cancer cells in vitro. Higher expression levels of CD100 correlate with poor survival in soft tissue sarcoma patients.
ImmunogenPHA stimulated human PBL
Other NamesCOLL4, SEMA4D, semaphorin 4D
Gene, Accession #Gene ID: 10507, UniProt: Q92854
Catalog #orb1570908
Price$372
Order / More InfoCD100 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

http://www.biorbyt.com

U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558


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