MBP / Myelin Basic Protein Antibody from BIORBYT LTD.

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Antigenic SpecificityMBP / Myelin Basic Protein
ClonerMBP/4288
Host SpeciesRecombinant Mouse
Reactive Specieshuman
IsotypeIgG2a, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P, WB
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DescriptionMyelin basic protein (MBP) is the second most abundant protein in central nervous system (CNS) myelin: it comprises 30% of the total protein and about 10% of the dry weight of myelin. It is the only structural protein found so far to be essential for formation of CNS myelin, and has been called the executive molecule of myelin . MBP can interact with a number of polyanionic proteins including actin, tubulin, calmodulin, and clathrin, and negatively charged lipids, and acquires structure on binding to them. It may act as a membrane actin-binding protein, which might allow it to participate in transmission of extracellular signals to the cytoskeleton in oligodendrocytes and tight junctions in myelin. MBP may be applicable as a marker for oligodendrogliomas.
ImmunogenA portion of amino acids 150-250 from the human protein was used as the immunogen for the recombinant MBP antibody.
Other Namesn/a
Gene, Accession #UniProt: P02686
Catalog #orb699550
Price$764
Order / More InfoMBP / Myelin Basic Protein Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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