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Antigenic Specificity | CD294 |
Clone | BM16 |
Host Species | n/a |
Reactive Species | human |
Isotype | IgG2a |
Format | allophycocyanin (APC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD294 (prostaglandin D2 receptor 2) is a G-protein-coupled receptor that is preferentially expressed in CD4+ effector T helper 2 (Th2) cells, but also on eosinophils and basophils. It mediates the pro-inflammatory chemotaxis of eosinophils, basophils, and Th2 lymphocytes generated during allergic inflammation. Single nucleotide polymorphisms in the 3' UTR of CD294 gene have been associated with asthma susceptibility. Outside the immune system CD294 is expressed e.g. in gut, heart, and brain. The intracellular C terminal tail contains sites for phosphorylation by protein kinase C. |
Immunogen | Human CD294 transfected rat cell line TART/B19-12.10 |
Other Names | DP2, PTGDR2, DL1R, CRTH2, GPR44 |
Gene, Accession # | Gene ID: 11251, UniProt: Q9Y5Y4 |
Catalog # | orb1881233 |
Price | $439 |
Order / More Info | CD294 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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