MART-1 / Melan-A Antibody from BIORBYT LTD.
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| Antigenic Specificity | MART-1 / Melan-A |
| Clone | MLANA/4385R |
| Host Species | Recombinant Rabbit |
| Reactive Species | human |
| Isotype | IgG |
| Format | Protein A purified |
| Size | 20 ug, 100 ug |
| Concentration | n/a |
| Applications | IHC-P, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. |
| Immunogen | A recombinant fragment corresponding to the N-terminus of human Melan A was used as the immunogen for the recombinant MART-1 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q16655 |
| Catalog # | orb699795 |
| Price | $405 |
| Order / More Info | MART-1 / Melan-A Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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