CD18 / ITGB2 / LFA-1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | CD18 / ITGB2 / LFA-1 |
| Clone | 68-5A5 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | FACS, Functional Studies, IF |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | It recognizes a transmembrane glycoprotein of 95kDa, identified as CD18 or integrin -2 (Workshop III). It complexes non-covalently with either L, M, or X integrin (CD11a, b, or c) to form the heterodimers, LFA-1, Mac-1, and p150,95, respectively. LFA-1 is the receptor for three members of the Ig supergene family of proteins, ICAM-1 (CD54), ICAM-2 (CD102), and Mac-1 and p150,95 bind to ICAM-1, fibrinogen, and iC3b. ICAM-3 (CD50). CD18/CD11 heterodimeric molecules are involved with cell/cell and cell/extracellular adhesion in immune and inflammatory responses. This mAb blocks these cellular interactions. |
| Immunogen | Stimulated human leukocytes were used as the immunogen for the CD18 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P05107 |
| Catalog # | orb749614 |
| Price | $764 |
| Order / More Info | CD18 / ITGB2 / LFA-1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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