HDAC1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | HDAC1 |
| Clone | 1061CT1.3.1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM,κ |
| Format | unconjugated |
| Size | 400 ul, 80 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse monoclonal to HDAC1. Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium stimulation, HDAC1 is released from the complex and CREBBP is recruited, which facilitates transcriptional activation. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Deacetylates Lys-310 in RELA and thereby inhibits the transcriptional activity of NF-kappa-B. Component a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. |
| Immunogen | Recombinant Protein |
| Other Names | HDAC1, RPD3L1, Histone deacetylase 1 |
| Gene, Accession # | UniProt: Q13547 |
| Catalog # | orb106889 |
| Price | $561 |
| Order / More Info | HDAC1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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