Mitofusin 2 Antibody from BIORBYT LTD.
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| Antigenic Specificity | Mitofusin 2 |
| Clone | S153-5 |
| Host Species | Mouse |
| Reactive Species | human, mouse, rat |
| Isotype | IgG2a |
| Format | allophycocyanin (APC) conjugate |
| Size | 100 ug |
| Concentration | 1 mg/ml |
| Applications | ICC, IHC, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mouse monoclonal to Mitofusin 2 (APC). Mitofusin-2 (Mfn2) is a membrane protein of the mitochondria and is important in mitochondrial fusion in mammalian cells. Mfn2 activity has also been implicated in mitochondrial metabolism and the loss of Mfn2 may be the reason for certain metabolic modifications that are seen in individuals with obesity. Mfn2 has been associated with maintaining the membrane potential of the mitochondria. Mfn2 has been shown to hinder mitochondrial antiviral signaling by inhibiting production of type 1 interferons. Mfn2 is a p53-inducible target and involved in cell proliferation, apoptosis promotion and tumor suppression.. |
| Immunogen | Fusion protein amino acids 370-600 (cytoplasmic N-terminus) of mouse Mitofusin-2. Rat: 97% identity (226/231 amino acids identical). Human: 92% identity (214/231 amino acids identical) ~55% identity with Mitofusin-1. |
| Other Names | CMT2A, CMT2A2, CPRP 1, CPRP1, Fzo, HSG, hyperplasia suppressor gene, Hypertension related protein 1, KIAA0214, MARF, MFN 2, Mfn2, Mitochondrial assembly regulatory factor, Mitofusin-2, Mitofusin2, Transmembrane GTPase MFN2 |
| Gene, Accession # | Gene ID: 170731, UniProt: Q80U63 |
| Catalog # | orb150812 |
| Price | $572 |
| Order / More Info | Mitofusin 2 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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