Edit |   |
---|---|
Antigenic Specificity | Synaptotagmin-7 |
Clone | S275-14 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2B |
Format | ATTO-488 conjugate |
Size | 100 ug |
Concentration | 1 mg/ml |
Applications | ICC, IHC, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to Synaptotagmin-7 (ATTO-488). Synaptotagmins constitute a family of membrane trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first domain mediates Ca(2+)-dependent phospholipid Synaptotagmins constitute a family of membrane trafficking proteins that are characterized by an N-terminal transmembrane region (TMR), a variable linker, and two C-terminal C2 domains - C2A and C2B. There are 15 members in the mammalian synaptotagmin family. There are several C2-domain containing protein families that are related to synaptotagmins, including transmembrane (Ferlins, E-Syts, and MCTPs) and soluble (RIMs, Munc13s, synaptotagmin-related proteins and B/K) proteins. The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin participates in triggering neurotransmitter release at the synapse. The first domain mediates Ca(2+)-dependent phospholipid. |
Immunogen | Fusion protein amino acids 150-239 (Cytoplasmic C2A domain) of mouse Synaptotagmin-7 |
Other Names | IPCA-7, PCANAP7, Prostate cancer-associated protein 7, SYT-7, SYT7, Synaptotagmin 7, Synaptotagmin VII, SytVII |
Gene, Accession # | Gene ID: 54525, UniProt: Q9R0N7 |
Catalog # | orb150226 |
Price | $573 |
Order / More Info | Synaptotagmin-7 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558