MAGE-1 Antibody from BIORBYT LTD.

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Antigenic SpecificityMAGE-1
CloneMA454
Host SpeciesMouse
Reactive Specieshuman, rat
IsotypeIgG1, kappa
FormatProtein G purified
Size20 ug, 100 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionRecognizes a protein of 42-46kDa, identified as MAGE-1. This mAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
ImmunogenFull length human protein was used as the immunogen for this MAGE-1 antibody.
Other Namesn/a
Gene, Accession #UniProt: P43355
Catalog #orb385726
Price$405
Order / More InfoMAGE-1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

info@biorbyt.com

http://www.biorbyt.com

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Biorbyt LLC
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St Louis, MO 63132
Email: info@biorbyt.com
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