Edit |   |
---|---|
Antigenic Specificity | Semaphorin-4D / SEMA4D |
Clone | A8 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 20 ug, 100 ug |
Concentration | n/a |
Applications | FACS, Functional Studies, IF |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a homodimeric protein comprised of 50kDa subunits, identified as Semaphorin-4D, or CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation. |
Immunogen | PHA stimulated human peripheral blood lymphocytes were used as the immunogen for the Semaphorin-4D antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: Q92854 |
Catalog # | orb749459 |
Price | $405 |
Order / More Info | Semaphorin-4D / SEMA4D Antibody from BIORBYT LTD. |
Product Specific References | n/a |
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558