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Antigenic Specificity | HLA-E |
Clone | 3D12 |
Host Species | n/a |
Reactive Species | human |
Isotype | IgG1 |
Format | allophycocyanin (APC) conjugate |
Size | 0.1 mg |
Concentration | 0.1 mg/ml |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | HLA-E (human leukocyte antigen E) is a non-classical MHC I antigen, which is important for dialogue with NK cells and their regulation through interaction with CD94/NKG2 receptor. Like other MHC I molecules, transmembrane HLA-E molecule (45 kDa) associates with beta2 microglobulin. Unlike HLA-G, expression of HLA-E molecules is not so restricted, but it has been detected at least at mRNA level in virtually all cells and tissues examined. In peripheral blood, HLA-E protein is expressed at least in all mononuclear cells, but in different quantity (B cells and monocytes more than T cells and NK cells). |
Immunogen | recombinant human HLA-E |
Other Names | HLA class I histocompatibility antigen, alpha chain E, MHC class I antigen E |
Gene, Accession # | Gene ID: 3133, UniProt: P13747 |
Catalog # | orb1881244 |
Price | $543 |
Order / More Info | HLA-E Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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