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Antigenic Specificity | Retinoblastoma / Rb1 |
Clone | SPM353 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes a 105kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma. |
Immunogen | A human recombinant partial protein was used as the immunogen for this Retinoblastoma antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P06400 |
Catalog # | orb386169 |
Price | $764 |
Order / More Info | Retinoblastoma / Rb1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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