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Antigenic Specificity | Integrin alpha E / CD103 |
Clone | ITGAE/2474 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E-beta-7 integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. This antibody is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL). |
Immunogen | A portion of amino acids 775-855 from the human protein was used as the immunogen for the CD103 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P38570 |
Catalog # | orb606581 |
Price | $764 |
Order / More Info | Integrin alpha E / CD103 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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