Edit |   |
---|---|
Antigenic Specificity | PIDD |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | 100 µg/ml BSA |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to PIDD. P53-induced protein with a death domain (PIDD ) promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. PIDD associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. PIDD also associates with CASP2/caspase-2 and CRADD/RAIDD, and induces activation of CASP2 which is an important regulator in apoptotic pathway. |
Immunogen | C-terminal region of human PIDD |
Other Names | n/a |
Gene, Accession # | UniProt: Q9HB75 |
Catalog # | orb131777 |
Price | $462 |
Order / More Info | PIDD Antibody from BIORBYT LTD. |
Product Specific References | n/a |
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558