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Antigenic Specificity | SQSTM1/p62 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Autophagy receptor that interacts directly with both the cargo to become degraded and an autophagy modifier of the MAP1 LC3 family. Required both for the formation and autophagic degradation of polyubiquitin-containing bodies, called ALIS (aggresome-like induced structures) and links ALIS to the autophagic machinery. Involved in midbody ring degradation. May regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. |
Immunogen | A synthetic peptide corresponding to residues surrounding Pro220 of human SQSTM1 protein. |
Other Names | p60; p62; A170; DMRV; OSIL; PDB3; ZIP3; p62B; NADGP; FTDALS3 |
Gene, Accession # | Gene ID: 8878, UniProt: Q13501 |
Catalog # | orb1729705 |
Price | $296 |
Order / More Info | SQSTM1/p62 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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