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Antigenic Specificity | S100A9 / MRP14 / Calgranulin B / Calprotectin L1H |
Clone | PS1A9-1 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgM, kappa |
Format | PEG purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | S100A9, also known as Calgranulin B or MRP14 (and Calprotectin L1H), is a calcium- and zinc-binding protein which plays a prominent role in the regulation of inflammatory processes and immune response. It can induce neutrophil chemotaxis, adhesion, can increase the bactericidal activity of neutrophils by promoting phagocytosis via activation of SYK, PI3K/AKT, and ERK1/2 and can induce degranulation of neutrophils by a MAPK-dependent mechanism. Predominantly found as calprotectin (S100A8/A9) which has a wide plethora of intra- and extracellular functions. The intracellular functions include: facilitating leukocyte arachidonic acid trafficking and metabolism, modulation of the tubulin-dependent cytoskeleton during migration of phagocytes and activation of the neutrophilic NADPH-oxidase. [UniProt] |
Immunogen | Recombinant human protein was used as the immunogen for the S100A9 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P06702 |
Catalog # | orb750149 |
Price | $764 |
Order / More Info | S100A9 / MRP14 / Calgranulin B / Calprotectin L1H Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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