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Antigenic Specificity | NECAB1 / N-terminal EF-hand calcium binding protein 1 |
Clone | NECAB1/7676 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | 100 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Members of the EF-CBP (N-terminal EF-hand calcium binding protein)/NECAB (neuronal calcium-binding protein) family participate in neuronal calcium signaling. EF-CBP1 (N-terminal EF-hand calcium binding protein 1), also known as STIP-1 or neuronal calcium-binding protein 1 (NECAB1), is a 351 amino acid cytoplasmic protein that contains one antibiotic biosynthesis monooxygenase (ABM) domain and 2 EF-hand domains. Expressed in brain, EF-CBP1 interacts with copine 6 and Syntaxin, and exists as two alternatively spliced isoforms. The gene encoding EF-CBP1 maps to human chromosome 8, which consists of nearly 146 million base pairs, encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that map to chromosome 8. |
Immunogen | Recombinant human NECAB1 protein was used as the immunogen for the N-terminal EF-hand calcium binding protein 1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: Q8N987 |
Catalog # | orb1822861 |
Price | $764 |
Order / More Info | NECAB1 / N-terminal EF-hand calcium binding protein 1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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