Granzyme A Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Granzyme A antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | Granzyme A |
| Clone | CB9 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 kappa |
| Format | Protein A purified |
| Size | 0.1 mg |
| Concentration | 1 mg/ml |
| Applications | FC, ICC, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Granzyme A is a serine protease expressed in the cytoplasmic granules of T cells and NK cells. Vectorial secretion of perforin and granzymes is responsible for their granule-mediated cytotoxicity. Similarly to granzyme B, granzyme A acts to destroy the target cells by proteolysis of their particular components. In case of granzyme A the targets are e.g. APEX1 (it destroys its oxidative repair activity), and nucleosome assembly protein SET (it disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA). |
| Immunogen | Full length human granzyme A |
| Other Names | HFSP, CTLA3, GrA |
| Gene, Accession # | Gene ID: 3001, UniProt: P12544 |
| Catalog # | orb1088500 |
| Price | $304 |
| Order / More Info | Granzyme A Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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