Myogenin / MYOG Antibody from BIORBYT LTD.

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Antigenic SpecificityMyogenin / MYOG
CloneMGN185
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1, kappa
FormatProtein G purified
Size100 ug, 20 ug
Concentrationn/a
ApplicationsIHC-P
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DescriptionMyogenin is a member of the MyoD family of myogenic basic helix-loop-helix (bHLH) transcription factors that also includes MyoD, Myf-5, and MRF4 (also known as herculinor Myf-6). MyoD family members are expressed exclusively in skeletal muscle and play a key role in activating myogenesis by binding to enhancer sequences of muscle-specific genes. The regulatory domain of MyoD is approximately 70 amino acids in length and includes both a basic DNA binding motif and a bHLH dimerization motif. MyoD family members share about 80% amino acid homology in their bHLH motifs. Myogenin antibody labels the nuclei of myoblasts in developing muscle tissue, and is expressed in tumor cell nuclei of rhabdomyosarcoma and some leiomyosarcomas. Positive nuclear staining may occur in Wilms' tumor.
ImmunogenHuman myogenin recombinant protein was used as the immunogen for this antibody.
Other Namesn/a
Gene, Accession #Gene ID: 4656, UniProt: P15173
Catalog #orb248476
Price$764
Order / More InfoMyogenin / MYOG Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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