ABO (Blood Group Antigen A) Antibody from BIORBYT LTD.
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| Antigenic Specificity | ABO (Blood Group Antigen A) |
| Clone | HE-10 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgM, kappa |
| Format | PEG purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | HAI, IF, IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This mAb preferably reacts with determinants of chain A and H type 3 (Gal1-3GalNAc-R) and 4 (Gal1-3GalNAc-R), but not with type 1 and 2 chain structures. It is not reactive with immuno-dominant A trisaccharide. This mAb is applicable for tissue staining in tumor patients with blood groups A and AB. It shows a highly heterogeneous reactivity in human colon tumor tissue and adjacent mucosa. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. |
| Immunogen | A mixture of erythrocytes of blood group A and glycoprotein fraction isolated from the saliva of secretors with blood group A was used as the immunogen for the ABO antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P16442 |
| Catalog # | orb749543 |
| Price | $764 |
| Order / More Info | ABO (Blood Group Antigen A) Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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