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Antigenic Specificity | CDH1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to CDH1.Cadherin-1 (CDH1) is a single-pass membrane protein. Cadherins are calcium-dependent celladhesion proteins. They preferentially interact with themselves in a homophilic manner in connectingcells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved inmechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. It has a potentinvasive suppressor role. It is a ligand for integrin alpha-E/beta-7. Defects in CDH1 are the cause ofhereditary diffuse gastric cancer (HDGC) and are a cause of susceptibility to endometrial cancer(ENDMC) and ovarian cancer (OC). |
Immunogen | C-terminal region of human CDH1 |
Other Names | CDH1,Cadherin1,CAM 120,80,Epithelial cadherin,Ecadherin,Uvomorulin,CD324,CDHE,UVO |
Gene, Accession # | UniProt: P12830 |
Catalog # | orb66765 |
Price | $527 |
Order / More Info | CDH1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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