CASP10 Antibody from BIORBYT LTD.
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| Edit | |
|---|---|
| Antigenic Specificity | CASP10 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to CASP10.Caspase 10 (CASP10) belongs to the peptidase C14A family, which is involved in the activationcascade of caspases responsible for apoptosis execution. CASP10 is recruited to both Fas-andTNFR-1 receptors in a FADD dependent manner, and may participate in the granzyme B apoptoticpathways. CASP10 cleaves and activates caspase-3, -4, -6, -7, -8, and -9, and hydrolyzes the smallmoleculesubstrates, Tyr-Val-Ala-Asp-|-AMC and Asp-Glu-Val-Asp-|-AMC. Defects in CASP10 havebeen implicated in autoimmune lymphoproliferative syndrome type 2A (ALPS2A), familial non-Hodgkin lymphoma (NHL) and gastric cancer (GASC). |
| Immunogen | middle region of human CASP10 |
| Other Names | CASP10,Caspase10,CASP10,Apoptotic protease Mch4,MCH4,FASassociated death domain proteininterleukin1Bconverting enzyme 2,FLICE2,ICElike apoptotic protease 4 |
| Gene, Accession # | UniProt: Q92851 |
| Catalog # | orb66964 |
| Price | $527 |
| Order / More Info | CASP10 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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