CD79a Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-CD79a antibody, protein, ELISA kits.
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| Antigenic Specificity | CD79a |
| Clone | HM47 |
| Host Species | n/a |
| Reactive Species | bovine, canine, equine, chicken, guinea pig, human, mouse, porcine, primate, rabbit, rat |
| Isotype | IgG1 kappa |
| Format | fluorescein (FITC) conjugate |
| Size | 100 tests |
| Concentration | n/a |
| Applications | FC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD79a (Ig alpha, MB1) forms disulfide-linked heterodimer with CD79b (Ig beta). They both are transmembrane proteins with extended cytoplasmic domains containing immunoreceptor tyrosine activation motives (ITAMs), and together with cell surface immunoglobulin they constitute B-cell antigen-specific receptor (BCR). CD79a and b are the first components of BCR that are expressed developmentally. They appear on pro-B cells in association with the endoplasmic reticulum chaperone calnexin. Subsequently, in pre-B cells, CD79 heterodimer is associated with lambda5-VpreB surrogate immunoglobulin and later with antigen-specific surface immunoglobulins. At the plasma cell stage, CD79a is present as an intracellular component. CD79a/b complex interacts with Src-family tyrosine kinase Lyn, which phosphorylates its cytoplasmic ITAM motives to form docking sites for downstream signaling. |
| Immunogen | Synthetic peptide corresponding to C terminal amino acids 208-222 of human CD79a |
| Other Names | BCR alpha, Ig-alpha, MB-1, IGA |
| Gene, Accession # | Gene ID: 973, UniProt: P11912 |
| Catalog # | orb1821019 |
| Price | $372 |
| Order / More Info | CD79a Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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