AKT1 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-AKT1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | AKT1 |
| Clone | 3A3 |
| Host Species | Mouse |
| Reactive Species | human, monkey, mouse |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | ELISA, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Multiple alternatively spliced transcript variants have been found for this gene. |
| Immunogen | Purified recombinant fragment of human AKT1 expressed in E. Coli. |
| Other Names | AKT; PKB; RAC; PRKBA; MGC99656; PKB-ALPHA; RAC-ALPHA; AKT1 |
| Gene, Accession # | Gene ID: 207 |
| Catalog # | orb1733213 |
| Price | $345 |
| Order / More Info | AKT1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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