Nitrotyrosine Antibody from BIORBYT LTD.

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Antigenic SpecificityNitrotyrosine
Clone39B6
Host SpeciesMouse
Reactive Speciesn/a
IsotypeIgG2a
FormatATTO-594 conjugate
Size100 ug
Concentration1 mg/ml
ApplicationsAM, ELISA, FC, ICC, IHC, IP, WB
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DescriptionMouse monoclonal to Nitrotyrosine (ATTO-594). Protein tyrosine nitration results in a post-translational modification that is increasingly receiving attention as an important component of nitric oxide signaling. While multiple nonenzymatic mechanisms are known to be capable of producing nitrated tyrosine residues, most tyrosine nitration events involve catalysis by metalloproteins such as myeloperoxidase, eosino-philperoxidase, myoglobin, the cytochrome P-450s, superoxide dismutase and prostacyclin synthase. Nitrotyrosine may also serve as a biomarker for the effects of reactive nitrogen oxides, based on tyrosine residues becoming nitrated in proteins at sites of inflammation induced tissue injury. The presence of nitro tyrosine-containing proteins therefore has shown high correlation to disease states such as atherosclerosis, Alzheimers disease, Parkinsons disease and amyotrophic lateral sclerosis..
Immunogen3-(4-hydroxy-3-nitrophenylacetamido) propionic acid-bovine serum albumin
Other NamesNitro tyrosine, 3-Nitrotyrosine
Gene, Accession #n/a
Catalog #orb147391
Price$591
Order / More InfoNitrotyrosine Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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