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Antigenic Specificity | HP1a |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 100 ul |
Concentration | n/a |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit polyclonal to HP1a.Heterochromatin protein 1-alpha (HP1a) is a highly conserved nonhistone protein belonging to theheterochromatin protein family. The N-terminal chromodomain of HP1a binds to histone H3 tailsmethylated at Lys-9 (H3K9me), leading to epigenetic repression. Conversely, it is excluded fromchromatin when Tyr-41 of histone H3 is phosphorylated (H3Y41ph). It may interact with lamin-Breceptor. HP1a is involved in the formation of functional kinetochore through interaction with MIS12complex proteins. |
Immunogen | middle region of mouse HP1a |
Other Names | HP1a,Cbx5,HP1,2610029O15Rik,C75991 |
Gene, Accession # | UniProt: Q61686 |
Catalog # | orb66782 |
Price | $527 |
Order / More Info | HP1a Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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