Beta-2 Microglobulin Antibody from BIORBYT LTD.
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| Antigenic Specificity | Beta-2 Microglobulin |
| Clone | rB2M/961 |
| Host Species | Recombinant Mouse |
| Reactive Species | human |
| Isotype | IgG2b, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | FACS, IF, IHC-P, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes a protein of 12kDa, identified as beta-2 microglobulin. Major histocompatibility complex (MHC) class 1 molecules bind to antigens for presentation on the surface of cells. The proteasome is responsible for producing these antigens from the components of foreign pathogens. MHC class 1 molecules consist of an alpha heavy chain that contains three subdomains (alpha1, alpha2, alpha3) and a non-covalent associating light chain, known as beta-2-Microglobulin. Beta-2-Microglobulin associates with the alpha3 subdomain of the alpha heavy chain and forms an immunoglobulin domain-like structure that mediates proper folding and expression of MHC class 1 molecules. The alpha1 and alpha2 domains of the alpha heavy chain form the peptide antigen-binding cleft. Mutations in the beta-2-Microglobulin gene can enhance the progression of malignant melanoma phenotypes. |
| Immunogen | Full length recombinant human protein was used as the immunogen for the recombinant Beta-2 Microglobulin antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P61769 |
| Catalog # | orb606368 |
| Price | $764 |
| Order / More Info | Beta-2 Microglobulin Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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