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Antigenic Specificity | SMARCAL1 |
Clone | PCRP-SMARCAL1-1C4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2c, kappa |
Format | unconjugated |
Size | 20 ug |
Concentration | n/a |
Applications | IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SmarcAL1 (SWI/SNF-related matrix-associated Actin-dependent regulator of chromatin subfamily A-like protein 1), also known as HARP (hepA-related protein) or HHARP, is a 954 amino acid member of the SWI/SNF family of helicase and ATPase proteins. Localized to the nucleus, SmarcAL1 is a ubiquitously expressed protein that functions in ATP-dependent nucleosomeremodeling activities. SmarcAL1 contains one conserved C-terminal SNF2 domain, one helicase ATP-binding domain and two HARP domains. Defects in the gene encoding SmarcAL1 are the cause of Schimke immuno-osseous dysplasia (SIOD), an autosomal recessive disorder characterized by renal dysfunction, spondyloepiphyseal dysplasia and T cell immunodeficiency. |
Immunogen | Recombinant full-length human SMARCAL1 protein was used as the immunogen for the SMARCAL1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: Q9NZC9 |
Catalog # | orb1823781 |
Price | $405 |
Order / More Info | SMARCAL1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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