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Antigenic Specificity | EYA1/4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | unconjugated |
Size | 100 ul |
Concentration | n/a |
Applications | ELISA, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Functions both as protein phosphatase and as transcriptional coactivator for SIX1, and probably also for SIX2, SIX4 and SIX5 (By similarity). Tyrosine phosphatase that dephosphorylates 'Tyr-142' of histone H2AX (H2AXY142ph) and promotes efficient DNA repair via the recruitment of DNA repair complexes containing MDC1. 'Tyr-142' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. |
Immunogen | Synthetic peptide from human protein at AA range: 271-320 |
Other Names | Eyes absent homolog 1; Eyes absent homolog 4 |
Gene, Accession # | Gene ID: 2070, UniProt: O95677 |
Catalog # | orb1730033 |
Price | $296 |
Order / More Info | EYA1/4 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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