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Antigenic Specificity | PAIP1 |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | ICC, IHC, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. |
Immunogen | A synthetic peptide of human PAIP1 |
Other Names | poly(A) binding protein interacting protein 1 |
Gene, Accession # | Gene ID: 10605, UniProt: Q9H074 |
Catalog # | orb1731563 |
Price | $345 |
Order / More Info | PAIP1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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