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Antigenic Specificity | Cyclin D1 / CCND1 |
Clone | SPM587 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG2a, kappa |
Format | Protein G purified |
Size | 100 ug, 20 ug |
Concentration | n/a |
Applications | FACS, IHC-P, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cyclin D1 (CCND1), one of the key cell cycle regulators, is a putative proto-oncogene overexpressed in a wide variety of human neoplasms. About 60% of mantle cell lymphomas (MCL) contain a t(11; 14)(q13; q32) translocation resulting in over-expression of Cyclin D1. This antibody is useful in identifying mantle cell lymphomas (CCND1+) from CLL/SLL and follicular lymphomas (CCND1-). Occasionally, hairy cell leukemia and plasma cell myeloma weakly express CCND1. |
Immunogen | Recombinant full length human protein was used as the immunogen for this CCND1 antibody. |
Other Names | n/a |
Gene, Accession # | UniProt: P24385 |
Catalog # | orb750252 |
Price | $764 |
Order / More Info | Cyclin D1 / CCND1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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