TNFSF15 / VEGI / TL1A Antibody from BIORBYT LTD.
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|---|---|
| Antigenic Specificity | TNFSF15 / VEGI / TL1A |
| Clone | TLRM1-1 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Vascular endothelial growth inhibitor (VEGI), also known as TNF-like ligand 1A (TL1A) and TNF superfamily member 15 (TNFSF15), is protein that in humans is encoded by the TNFSF15 gene. TL1A/VEGI is an anti-angiogenic protein. It belongs to tumor necrosis factor (ligand) superfamily, where it is member 15. It is the sole known ligand for death receptor 3, and it can also be recognized by decoy receptor 3.TL1A is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF-alpha and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 (death receptor 3) and TNFRSF6B (decoy receptor 3). It can activate both the NF-κB and MAPK signalling pathways, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. [Wiki] |
| Immunogen | A full length human recombinant protein was used as the immunogen for this TL1A antibody. |
| Other Names | n/a |
| Gene, Accession # | Gene ID: 9966, UniProt: O95150 |
| Catalog # | orb376640 |
| Price | $764 |
| Order / More Info | TNFSF15 / VEGI / TL1A Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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