MMP3 / Matrix Metalloproteinase 3 Antibody from BIORBYT LTD.
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| Antigenic Specificity | MMP3 / Matrix Metalloproteinase 3 |
| Clone | 1B4 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, lambda |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | ELISA |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. |
| Immunogen | Amino acids 317-327 from the human protein were used as the immunogen for this Matrix Metalloproteinase 3 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P08254 |
| Catalog # | orb639814 |
| Price | $764 |
| Order / More Info | MMP3 / Matrix Metalloproteinase 3 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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