HP1 alpha Antibody from BIORBYT LTD.

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Antigenic SpecificityHP1 alpha
Clone12F8
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatunconjugated
Size100 ul
Concentration1mg/ml
ApplicationsIHC, WB
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DescriptionComponent of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
ImmunogenPurified recombinant protein expressed in E.coli.
Other NamesCBX5; HP1A; Chromobox protein homolog 5; Antigen p25; Heterochromatin protein 1 homolog alpha; HP1 alpha
Gene, Accession #Gene ID: 23468, UniProt: P45973
Catalog #orb1732669
Price$345
Order / More InfoHP1 alpha Antibody from BIORBYT LTD.
Product Specific Referencesn/a
BIORBYT LTD.
BIORBYT LTD.
BIORBYT LTD.
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Swann Road
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P: +44 (0)1223 859 353
F: +44(0)1223 280 240

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