14-3-3 epsilon / YWHAE Antibody from BIORBYT LTD.
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| Antigenic Specificity | 14-3-3 epsilon / YWHAE |
| Clone | rYWHAE/8860 |
| Host Species | Recombinant Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathway. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. The YWHAE gene which encodes 14-3-3E has also been identified as a possible susceptibility gene for schizophrenia. |
| Immunogen | Recombinant human full-length protein was used as the immunogen for the recombinant YWHAE antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: P62258 |
| Catalog # | orb1825197 |
| Price | $405 |
| Order / More Info | 14-3-3 epsilon / YWHAE Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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