Homer1 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Homer1 antibody, protein, ELISA kits.
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| Antigenic Specificity | Homer1 |
| Clone | monoclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | IgG |
| Format | unconjugated |
| Size | 100 ul |
| Concentration | 1mg/ml |
| Applications | IP, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Postsynaptic density scaffolding protein. Binds and cross-links cytoplasmic regions of GRM1, GRM5, ITPR1, DNM3, RYR1, RYR2, SHANK1 and SHANK3. By physically linking GRM1 and GRM5 with ER-associated ITPR1 receptors, it aids the coupling of surface receptors to intracellular calcium release. May also couple GRM1 to PI3 kinase through its interaction with AGAP2. Isoform 1 regulates the trafficking and surface expression of GRM5. Isoform 3 acts as a natural dominant negative, in dynamic competition with constitutively expressed isoform 1 to regulate synaptic metabotropic glutamate function. Isoform 3, may be involved in the structural changes that occur at synapses during long-lasting neuronal plasticity and development. Forms a high-order complex with SHANK1, which in turn is necessary for the structural and functional integrity of dendritic spines . |
| Immunogen | Recombinant protein of human Homer1 |
| Other Names | HOMER; SYN47; Ves-1; HOMER1A; HOMER1B; HOMER1C |
| Gene, Accession # | Gene ID: 9456, UniProt: Q86YM7 |
| Catalog # | orb1731848 |
| Price | $345 |
| Order / More Info | Homer1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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