MALT1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | MALT1 |
| Clone | SPM578 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | Protein G purified |
| Size | 100 ug, 20 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Mucosa associated lymphoid tissue lymphoma translocation gene 1 (MALT-1) is found in extranodal low-grade B cell lymphomas. The gene encodes two Ig-like C2-type domains and fuses with an API2 gene, which is highly expressed in adult lymphoid tissue. The translocation of this MALT-1 gene and the apoptosis-inhibiting API2 gene results in an increased development of MALT lymphomas and apoptosis inhibition. Sites at which this API2-MALT1 (11;18)(q21;q21) translocation commonly occurs are within human lung and kidney tissue. MALT lymphoma expresses nuclear Bcl10, which mediates the oligomerization and activation of a MALT-1 caspase-like domain. MALT-1 mRNA is found in pre-B cells, mature B cells and plasma cells. |
| Immunogen | Amino acids 701-808 from the human protein were used as the immunogen for this MALT1 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q9UDY8 |
| Catalog # | orb750190 |
| Price | $764 |
| Order / More Info | MALT1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
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