Periostin Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-Periostin antibody, protein, ELISA kits.
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|---|---|
| Antigenic Specificity | Periostin |
| Clone | rPOSTN/8522 |
| Host Species | Recombinant Mouse |
| Reactive Species | human |
| Isotype | IgG1, kappa |
| Format | unconjugated |
| Size | 100 ug |
| Concentration | n/a |
| Applications | IHC-P |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Periostin (PN), also designated osteoblast-specific factor 2 (OSF-2), is a disulfide linked protein originally isolated as a osteoblast-specific factor. Periostin is a secreted protein that binds heparin and functions as a ligand for AlphaVBeta3 and AlphaVBeta5 integrins. In preosteoblasts, Periostin acts as a cell adhesion molecule and plays a role in osteoblast recruitment, spreading and attachment. Periostin is mainly detected in lower gastrointestinal tract, aorta, stomach, placenta, uterus and breast tissues but is up-regulated in epithelial ovarian tumors and overexpressed in breast cancer. Expression of Periostin is increased by bone morphogenetic protein (BMP2) and transforming growth factor Beta 1 (TGF Beta 1). Periostin contains a typical signal sequence, followed by a cysteine-rich domain, a fourfold repeated domain, which shows homology with the insect protein fasciclin, and a C-terminal domain. |
| Immunogen | A recombinant partial protein sequence (within amino acids 193-326) from the human protein was used as the immunogen for the recombinant POSTN antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q15063 |
| Catalog # | orb1825651 |
| Price | $764 |
| Order / More Info | Periostin Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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