DACH1 Antibody from BIORBYT LTD.
Search, find, compare suppliers for anti-DACH1 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | DACH1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 100 ul |
| Concentration | n/a |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to DACH1.Dachshund homolog 1 (DACH1) is a transcription factor involved in regulation of organogenesis. Itappears to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cellproliferation in myoblasts by SIX1 is switched to coactivation through recruient of EYA3 to the SIX1-DACH1 complex. DACH1 may act as a corepressor of SIX6 in regulating proliferation by directlyrepressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. It also inhibits TGFbetasignaling through interaction with SMAD4 and NCOR1 and binding to chromatin DNA via theDACHbox-N domain. Expression of DACH1 is lost in certain forms of metastatic cancer, and iscorrelated with poor prognosis. |
| Immunogen | C-terminal region of human DACH1 |
| Other Names | DACH1,Dachshund homolog 1,DACH |
| Gene, Accession # | UniProt: Q9UI36 |
| Catalog # | orb67117 |
| Price | $527 |
| Order / More Info | DACH1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
BIORBYT LTD.
7 Signet Court
Swann Road
Cambridge, CB5 8LA U.K.
P: +44 (0)1223 859 353
F: +44(0)1223 280 240
info@biorbyt.com
http://www.biorbyt.com
U.S. OFFICE
Biorbyt LLC
1100 Corporate Square Drive
Helix Center, Suite 221
St Louis, MO 63132
Email: info@biorbyt.com
Phone: +1 (415) 906-5211
Fax: +1 (415) 651-8558
Profile of BIORBYT LTD.
Return to Antibodies