Kindlin-1 / KIND1 Antibody from BIORBYT LTD.
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| Antigenic Specificity | Kindlin-1 / KIND1 |
| Clone | 4A5.14 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2a |
| Format | Protein G purified |
| Size | 20 ug, 100 ug |
| Concentration | n/a |
| Applications | IHC-P, WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Kindlin-1 (also known as KIND1, KINDLERIN, UNC112-RELATED PROTEIN 1 (URP1) is an important component of cell-extracellular matrix adhesion. Kindlin-1 is involved in cell adhesion, possibly via its interaction with integrins and may mediate TGF-beta 1 signaling during tumor progression. Kindlin-1 has been shown to be significantly upregulated in lung and colon carcinomas. Mutations in the kindlin-1 gene, FERMT1, causes Kindler syndrome. Kindler syndrome is an autosomal recessive disorder characterized by neonatal blistering, sun sensitivity, atrophy, abnormal pigmentation and fragility of the skin. We have developed monoclonal anti-kidlin-1 antibodies. This monoclonal antibody recognizes kindlin-1 in multiple assays including Western blotting, immunoprecipitation, immunohistochemical and immunofluorescent staining. |
| Immunogen | Amino acids 216-677 from the human protein were used as the immunogen for the Kindlin-1 antibody. |
| Other Names | n/a |
| Gene, Accession # | UniProt: Q9BQL6 |
| Catalog # | orb699654 |
| Price | $405 |
| Order / More Info | Kindlin-1 / KIND1 Antibody from BIORBYT LTD. |
| Product Specific References | n/a |
BIORBYT LTD.
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