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Antigenic Specificity | RAGE |
Clone | monoclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | IgG |
Format | unconjugated |
Size | 100 ul |
Concentration | 1mg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The receptor for advanced glycation end products (RAGE) is member of the immunoglobulin (Ig) superfamily. Mediates interactions of advanced glycosylation end products (AGE). Binding of AGEs to RAGE results in the induction of cellular oxidant stress and activation of the transcription factor NFkB. Evidence suggests that the induction of oxidant stress results in the activation of an intracellular cascade involving p21 ras and MAP kinase, which leads to activation of transcription. |
Immunogen | A synthetic peptide of human RAGE |
Other Names | AGER; RAGE; Advanced glycosylation end product-specific receptor; Receptor for advanced glycosylation end products |
Gene, Accession # | Gene ID: 177, UniProt: Q15109 |
Catalog # | orb1731441 |
Price | $345 |
Order / More Info | RAGE Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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